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March 31, 2023

Herpes Simplex Virus Type 2 (HSV-2) Infection

  • Qusai Alitter M.D
  • Case Reports
A seventy-year-old African American female with a past medical history of essential hypertension, type two diabetes mellitus, gout, and osteoarthritis presented to the hospital with complaints of pruritic skin rash around the eyes, diarrhea, and weakness. The patient was started on allopurinol a few weeks prior to presentation after an acute gout flare in the right foot. Patient had an oral temperature of 103 ˝F, a maculopapular rash of the face, eyelids, torso, and extremities, and diffuse tenderness with palpation of the abdomen.

Dare to DAIR: Is Rifampin Always Necessary?

  • John Segreti
  • Editorial
The treatment of early post-operative staphylococcal prosthetic joint infection (PJI) with debridement, antibiotics, and retention of the implant (DAIR) is becoming increasingly common. This approach has many advantages, primarily more rapid mobilization and return to normal activities compared to a one- or two-stage revision.

Specific Antibody Deficiency

  • Russell M. Petrak, MD
  • Review
Specific antibody deficiency was previously known as selective antibody deficiency with normal immunoglobulins (SADNI). The diagnosis of SAD depends on normal immunoglobulin and IgG subclass levels, as well as a normal reaction to protein-based and conjugate vaccinations. The only immunologic deficiency in patients with SAD is an abnormal response to polysaccharide antigens, as found in the PPV23, known as the twenty-three valent pneumococcal vaccine.

A Case of Triple-Infection with SARS-CoV-2, Chikungunya, and Dengue Fever in a Returning Traveler

  • Sally Arif, PharmD
  • Case Reports
A 39-year-old woman presented to the emergency department (ED) four days after returning from a 5-day-long trip to The Gambia in West Africa with complaints of fever, nausea, anorexia, and fatigue. The onset of symptoms started two days after her return to the United States.
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