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Specific Antibody Deficiency

Questions related to PPID article on Specific Antibody Deficiency.

20%

1 / 5

1. What levels are abnormal in specific antibody deficiency?

A. Quantitative immunoglobulins
B. IgG subsets
C. Response to protein based vaccine
D. Response to conjugate vaccines
E. Response to polysaccharide antigens

Explanation : Correct answer is E. Response to polysaccharide antigens.

40%

2 / 5

2. What are the most common infections seen in SAD?

A. Skin and soft tissue infection
B. Urinary tract infection
C. Upper/lower respiratory infection
D. Intra-abdominal infection

Explanation : Correct answer is C. Upper/lower respiratory infection.

60%

3 / 5

3. What are the most common bacteria leading to invasive infections in SAD?

A. S. pneumoniae
B. H. influenzae
C. Neisseria species
D. All of the above

Explanation : Correct answer is D. All of the above.

80%

4 / 5

4. What other diagnoses are associated with polysaccharide vaccine non-response similar to SAD?

A. IgG subclass deficiency
B. CVID
C. Ataxia telangiectasia
D. CLL
E. All of the above

Explanation : Correct answer is E. All of the above.

100%

5 / 5

5. Which of the following is considered a normal response to a polysaccharide antigen challenge?

A. Greater than 70% of PPSV titers above 1.3 mcg/mL post vaccination
B. Greater than 50% of PPSV titers above 1.3 mcg/mL post vaccination
C. Two fold increase from baseline titers after vaccination
D. Four fold increase from baseline titers after vaccination
E. A and C

Explanation : Correct answer is E. A and C.

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Board Review Questions

Specific Antibody Deficiency

1 / 5

1. What levels are abnormal in specific antibody deficiency?

2 / 5

2. What are the most common infections seen in SAD?

3 / 5

3. What are the most common bacteria leading to invasive infections in SAD?

4 / 5

4. What other diagnoses are associated with polysaccharide vaccine non-response similar to SAD?

5 / 5

5. Which of the following is considered a normal response to a polysaccharide antigen challenge?

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Board Review Questions

Specific Antibody Deficiency

1 / 5

1. What levels are abnormal in specific antibody deficiency?

2 / 5

2. What are the most common infections seen in SAD?

3 / 5

3. What are the most common bacteria leading to invasive infections in SAD?

4 / 5

4. What other diagnoses are associated with polysaccharide vaccine non-response similar to SAD?

5 / 5

5. Which of the following is considered a normal response to a polysaccharide antigen challenge?

Important Links

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